Date of Award

Spring 1981

Document Type



Life & Environmental Sciences

First Advisor

James Manion

Second Advisor

Rev. Joseph Harrington

Third Advisor

Gary Hoovestal


A solution of homogenized hind limb buds was used as a source of an inducing agent(s). This was placed in an artificial sheath, bridging the ends of the severed sciatic nerve axon of which a small portion was removed and which also served to maintain localization of the inducing agent(s). These experimentals were compared with a control group whose sheath contained amphibian ringer's solution. No correlation could be found from the data obtained. However, it is believed that these results do not directly reflect the hypothesis because of the number of variables involved.