Date of Award

Spring 1983

Document Type

Thesis

Department

Life & Environmental Sciences

First Advisor

Tom Fritz

Second Advisor

John Christenson

Third Advisor

James Manion

Abstract

The effects of lithium carbonate on granulopoiesis in the beagle dog and the protection offered these dogs from radiation-induced marrow injury were investigated. Comparisons were made between control and lithium-treated dogs concerning marrow granulocyte-committed colony forming units (CFU-c) and peripheral blood counts. The results did not support previous studies and demonstrated no enhancement of granulopoiesis in the lithium-treated dogs.

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