Date of Award

Spring 1983

Document Type

Thesis

Department

Life & Environmental Sciences

First Advisor

Maryanne Blunt

Second Advisor

John Christenson

Third Advisor

John Semmens

Abstract

Liver mitochondrial superoxide dismutase was purified from normally aging BIO and prematurely aging B1O.F mice. The specific activity of the enzyme was found to be lower in the prematurely aging strain. Further purification is necessary to be certain the difference in specific activities shown between the two strains of mice is valid. The congenic BIO and B1O.F strains may prove to be an ideal model for aging research.

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