Date of Award
Life & Environmental Sciences
Rev. Joseph Harrington
A growth curve was constructed for SCCVII-SF, a mouse squamous cell carcinoma cell line, in a culture of modified q-crle's medium. A toxicity curve was constructed for vincristine ,nd SCCVII-SF cells in the exponential phase of growth. Cells in mid-exponential phase were treated with a subtoxic level of vincristine for four hours. A count of mitotic cells was taken at intervals to determine whether vincristine caused a buildup of cells in mitosis after its removal. Results showed that cells continued to collect in mitosis for four hours after the removal of vincristine.
Firpo, Meri, "The Cytotoxic And Kinetic Effects Of Asynchronous Cells Following The Administration Of Vincristine" (1984). Life and Environmental Sciences Undergraduate Theses. 419.