Date of Award

Spring 2006

Document Type

Thesis

Department

Life & Environmental Sciences

First Advisor

Ron Wilde

Second Advisor

Dawn Bregel

Third Advisor

Kyle Strode

Abstract

The ability to study proteins and their role in cell function is a central area of scientific study. To learn more about proteins and glycosylation, a form of posttranslational modification, a means of detecting specifically for glycosylation is necessary. The modification of an existing dye to meet this need was the goal ofthe project. N-benzyl-4-nitroaniline and methyl ((4-(4-nitrophenyl)amino)methyl)benzoate, two intermediate compounds in the synthesis, were created and purified.

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