Date of Award

Spring 5-13-2017

Document Type



Life & Environmental Sciences


The fungus, Batrachochytrium dendrobatidis, has been found to negatively impact amphibian populations around the world. This fungus can have multiple effects on frog physiology, including changes in osmotic regulation that may lead to death. B. dendrobatidis has been shown to be the driving force for many amphibian population crashes and extinctions around the world. The purpose of this project was to build a predictive model of B. dendrobatidis infection, one that would be used to assess population susceptibility in order to identify populations of amphibians at risk of infection. This was accomplished by statistical analyses of several components that contribute to infection vulnerability, including amphibian antimicrobial peptide production, cutaneous bacterial colony structure, infection status for each frog and water nutrient composition. This project collected baseline data that will allow us to establish meaningful relationships between susceptibility factors and disease, which will permit the identification of populations at risk. Overall, it was found that variability within these nutrient factors, such as levels of phosphorus and manganese, as well as differences in AMP production and bacterial communities may have contributed to variations in infection status between lakes.