Lithium Carbonate Enhancement Of Granulopoiesis In The Beagle Dog

Abstract

The effects of lithium carbonate on granulopoiesis in the beagle dog and the protection offered these dogs from radiation-induced marrow injury were investigated. Comparisons were made between control and lithium-treated dogs concerning marrow granulocyte-committed colony forming units (CFU-c) and peripheral blood counts. The results did not support previous studies and demonstrated no enhancement of granulopoiesis in the lithium-treated dogs.