Valproic Acid In Epilepsy: Clinical And Adverse Effects

Loading...
Thumbnail Image
Authors
Siddoway, Paul
Advisor
Philip Pallister
James Manion
John Christenson
Editor
Date of Issue
1979-04-01
Subject Keywords
Publisher
Citation
Series/Report No.
item.page.identifier
Title
Valproic Acid In Epilepsy: Clinical And Adverse Effects
Other Titles
Type
thesis
Description
Abstract
The antiepileptic drug sodium valproate was studied in 19 epileptic patients with uncontrolled seizures of a generalized or partial type. Two-thirds of the patients experienced a reduction in seizure fre uency ranging from 33 to 100%. Adverse effects occurred in 7 (37%) patients and in 4 (21%) the drug had to be discontinued. The most serious adverse effects were platelet reduction and weight gain. Minor adverse effects (e.g. nausea, hair loss, SGOT elevation, ALKOP4 elevation) were always transient.
Sponsors
Degree Awarded
Bachelor's
Semester
Spring
Department
Life & Environmental Sciences