The Effects Of Nicotine On Dietary Atherogenesis In Mice

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Authors
Brooke, Daniel
Handwerk, Francis
Advisor
Jean Smith
James Manion
Guido Bugni
Editor
Date of Issue
1975-04-01
Subject Keywords
Publisher
Citation
Series/Report No.
item.page.identifier
Title
The Effects Of Nicotine On Dietary Atherogenesis In Mice
Other Titles
Type
thesis
Description
Abstract
Investigations Into the effects of nicotine on athero- genesis in mice were made. Four groups of mice were fed different diets for a period of four weeks and then sacrificed. Microscopic examination of the descending thoracic aorta revealed no presence of lesions. Analysis of test on the blood demonstrated lower levels of serum cholesterol in nicotine administered mice. Theories on nicotine and cholesterol involvement are discussed along with current ideas on the normal aortic aging process, the atherosclerotic process, and useful prophylactic measures.
Sponsors
Degree Awarded
Bachelor's
Semester
Spring
Department
Life & Environmental Sciences