Dose-Response Relationships Of Triethylenemelamine On Visible Chromosome Aberrations In Mouse Bone Marrow
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Authors
Watkins, John
Thennis, Nick
Date of Issue
1978-04-01
Type
thesis
Language
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Abstract
Cytogenetic analysis of mouse bone marrow chromosomes after treatment of the experimental animals with triethylenemelamine (TEM) revealed, an overall increase in the number of chromosome aberrations A dose-response curve for TEM is given and its significance discussed. An unexpected increase in the number of rings as well as a relatively constant value for the aberrations/oell ratio in each of three dosage groups (and control) were observed. Possible mechanisms are given attention.