Dose-Response Relationships Of Triethylenemelamine On Visible Chromosome Aberrations In Mouse Bone Marrow

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Authors
Watkins, John
Thennis, Nick
Advisor
James Manion
John Christenson
Guido Bugni
Editor
Date of Issue
1978-04-01
Subject Keywords
Publisher
Citation
Series/Report No.
item.page.identifier
Title
Dose-Response Relationships Of Triethylenemelamine On Visible Chromosome Aberrations In Mouse Bone Marrow
Other Titles
Type
thesis
Description
Abstract
Cytogenetic analysis of mouse bone marrow chromosomes after treatment of the experimental animals with triethylenemelamine (TEM) revealed, an overall increase in the number of chromosome aberrations A dose-response curve for TEM is given and its significance discussed. An unexpected increase in the number of rings as well as a relatively constant value for the aberrations/oell ratio in each of three dosage groups (and control) were observed. Possible mechanisms are given attention.
Sponsors
Degree Awarded
Bachelor's
Semester
Spring
Department
Life & Environmental Sciences