Illucidation Of Serum Gamma Globulins By Two-Dimensional Immunoelectrophoresis With Isogel

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Authors
Schemmel, Mark
Advisor
John Christenson
James Manion
Fr. Robert Butko
Editor
Date of Issue
1985-04-01
Subject Keywords
Publisher
Citation
Series/Report No.
item.page.identifier
Title
Illucidation Of Serum Gamma Globulins By Two-Dimensional Immunoelectrophoresis With Isogel
Other Titles
Type
thesis
Description
Abstract
This research project was designed to examine new possibilities for adapting two-dimensional immunoelectrophoresis to clinical situations, much as has been done with standard one-dimensional electrophoresis over the past several years. The hypothesis was that by using a gel medium with relatively no electroendosmosis, the immunoglobulins would become visible for evaluation with two-dimensional techniques. Results show that, although more work is necessary to refine the process, the immunoglobins do, indeed, become visible in two-dimensional assay procedures using this gel. This method shows a great deal of promise for future clinical acceptance of two-dimensional electrophoretic techniques.
Sponsors
Degree Awarded
Bachelor's
Semester
Spring
Department
Life & Environmental Sciences