Tumor Production in Mice by Sodium Saccharin

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Authors
Boespflug, Randy
King, John
Advisor
James Manion
John Christenson
Guido Bugni
Editor
Date of Issue
1976-04-01
Subject Keywords
Publisher
Citation
Series/Report No.
item.page.identifier
Title
Tumor Production in Mice by Sodium Saccharin
Other Titles
Type
thesis
Description
Abstract
Four groups of about 25 mice were fed 0%, 0.02%, 0.2% or 2% sodium saccharin (w/v) in their drinking water for up to 100 days. Two groups of 10 mice were injected with 0.2 ml or 4% or 8% sodium saccharin (w/v) interperitoneally. One group of 10 mice was given 0.2 ml of 8% sodium saccharin (w/v) subcutaneously. One group of 5 mice was given 0.2 ml of saturated saccharin subcutaneously. These groups were controlled with the administration of sterile normal saline in the corresponding amounts and manner. Significant enlargement of kidneys, hard-ened and reddened bladders and enlarged, distended, reddened uteri were observed.
Sponsors
Degree Awarded
Bachelor's
Semester
Spring
Department
Life & Environmental Sciences