Carotenoids and Their Effects on Macular Degeneration: a Systematic Review

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Authors
Bomengen, McKenna
Advisor
Schafer, Gerald
Editor
Date of Issue
2023-04-28
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Citation
Series/Report No.
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Title
Carotenoids and Their Effects on Macular Degeneration: a Systematic Review
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Type
Presentation
Description
Abstract
Objective: To review current literature concerning the effectiveness of lutein and carotenoid supplementation in preventing progression of Age-Related Macular Degeneration. Methods: Search engines PubMed and CIHNAL were used and further assessed for associations between the effectiveness of Lutein and the prevention of Macular Degeneration. The interventions included were AREDS, AREDS2, MaQuprev, lutein, zeaxanthin, vitamin C, vitamin E, beta carotene, zinc oxide, omega-3 long-chain polyunsaturated fatty acids, docosahexaenoic acid, eicosapentaenoic acid, and cupric oxide. Results: Most of the literature pointed to these treatments the slowing of ARMD progression. Two studies did not report slowing of ARMD when treated with combinations of carotenoids, vitamins, and other anti-inflammatory substances. Conclusion: Results were inconclusive. Not all studies reported significant figures supporting supplements in treatment of the slow of ARMD progression. Carotenoid interventions have shown promising results for the prevention of ARMD. The interventions mentioned in this review should be researched further to provide additional treatment options. Keywords: Age Related Macular Degeneration, Prevention, Lutein, Carotenoids
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Degree Awarded
Semester
Spring
Department
Health Sciences