The Effect of Per- and Polyfluoroalkyl Substances on Female Fertility: A Systematic Review
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Authors
Quigley, Madison
Date of Issue
2025-04-25
Type
Presentation
Language
en_US
Subject Keywords
Other Titles
Abstract
Objective: To review relevant literature on how per- and polyfluoroalkyl substances (PFAS) affect fertility in females.
Methods: Literature from PubMed and CINAHL databases were reviewed for associations between per- and polyfluoroalkyl substances and female fertility.
Results: The majority of studies found a negative association between PFAS exposure and infertility outcomes. However, not all PFAS exhibited adverse effects, and certain types positively affected fertility outcomes.
Conclusion: Certain PFAS, such as PFOA, have negative effects on fertility, but other types of PFAS, like small-chain PFAS, have positive effects. No conclusions can be drawn, and further research is needed.