A Study Of The Effects Of Caffeine On Thymus Gland Development And Birth Weight In Mice Of The BALB/c Strain

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Authors
Nye, Scott
Advisor
Rev. Joseph Harrington
John Addis
Henry Burgess
Editor
Date of Issue
1987-04-01
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Citation
Series/Report No.
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Title
A Study Of The Effects Of Caffeine On Thymus Gland Development And Birth Weight In Mice Of The BALB/c Strain
Other Titles
Type
thesis
Description
Abstract
Female mice of the BALB/c strain were injected with caffeine for fifty days, during which time they gave birth to two litters. Subcutaneous injections of a 0.84 mg/ml and a 1.68 mg/ml caffeine solution were given to the two experimental groups of females. The control group received injections of saline only. Thymus glands from the pups of the second set of litters bom were removed, weighed, and examined histologically. Birth weights of the pups were recorded. Comparative histological examination of the thymus glands reveals a higher epithelial reticular cell to T-lymphocyte ratio in the caffeine receiving groups. Statistical analysis of thymus gland and birth weights of the caffeine receiving groups shows a significant difference when compared to those of the controls.
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Degree Awarded
Bachelor's
Semester
Spring
Department
Life & Environmental Sciences