Screening for antibiotic, antifungal and antitumoral compounds in natural products extracted from freshwater sponges

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Authors
Daehnke, Danielle
Advisor
John Addis
Sam Alvey
Murphy Fox
Editor
Date of Issue
2006-04-01
Subject Keywords
freshwater sponge, Ephydatia muelleri, Eunapius fragilis, Spongilla lacustris
Publisher
Citation
Series/Report No.
item.page.identifier
Title
Screening for antibiotic, antifungal and antitumoral compounds in natural products extracted from freshwater sponges
Other Titles
Type
thesis
Description
Abstract
The secondary metabolites of marine sponges include many bioactive products (e.g., ara-C) that have found uses in the health field. Even though freshwater sponges share many characteristics with their marine cousins, little is known about their secondary metabolites. This study looks at the effects of the secondary metabolites extracted from three freshwater sponge species on the survival of bacteria, fungi and brine shrimp. It found that none of the extracts were toxic to the bacteria or fungi. Preliminary results did, however, show that all three species tested were active against the brine shrimp. This study suggests that the secondary metabolites of freshwater sponges should be tested more extensively to see if they contain useful bioactive compounds.
Sponsors
Degree Awarded
Bachelor's
Semester
Spring
Department
Life & Environmental Sciences