The Use of Dual Energy X-ray Absorptiometry to Study the Effects of Low-Dose Methotrexate on Bone Density
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Authors
Khaleel, Rubina
Advisor
John Christenson
Guido Bugni
Joan Stottlemyer
Guido Bugni
Joan Stottlemyer
Editor
Date of Issue
1996-04-01
Subject Keywords
Publisher
Citation
Series/Report No.
item.page.identifier
Title
The Use of Dual Energy X-ray Absorptiometry to Study the Effects of Low-Dose Methotrexate on Bone Density
Other Titles
Type
thesis
Description
Abstract
A study at Deaconess Research Institute was initiated to determine the contribution of low-dose Methotrexate to the development of osteopenia. Findings are based upon analysis of Dual Energy X-ray Absorptiometry (DEXA) scans for bone density and bone mass. Scans were performed 18 to 24 mo apart for 5 of 11 patients currently undergoing low-dose Methotrexate therapy for the treatment of rheumatoid arthritis. The results suggest there is no correlation between low-dosage Methotrexate and osteopenia/osteoporosis and that therapeutic doses seem to pose little threat of significant bone loss.
Sponsors
Degree Awarded
Bachelor's
Semester
Spring
Department
Life & Environmental Sciences