Supplementation of dietary sugars with non-nutritive sugars increases insulin sensitivity in patients with type II diabetes.

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Hague, Robert

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2024

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Objective: To review relevant literature regarding the consumption of non-nutritive sweeteners as an alternative to dietary sugars to help manage type II diabetes. Methods: Literature was gathered through PubMed and CINAHL in early 2024. Studies were reviewed to assess the effects that consumption of non-nutritive sweeteners (NNS) have on insulin resistance and blood sugar levels, when compared to dietary sugars. Results: The reviewed literature found that non-nutritive sweeteners can be used to help manage diabetes. Common NNS like aspartame and acesulfame resulted in small metabolic responses, leading to minimal increases in free insulin and blood sugar levels, when compared to physiological responses to dietary sugars. Conclusions: The use of NNS to manage insulin resistance in individuals with type II diabetes is possible. However, the studies reviewed were mostly short-term trials, there may be negative long-term side effects from longer uses of NNS. Given the increasing global burden of diabetes, further research on NNS is warranted. Keywords: non-nutritive sweeteners; sweetening agents; artificial sweeteners; type II diabetes; randomized controlled trial.

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