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    Site Specific Photoinitiated Release of Bromothymol Blue

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    Hoffman_Alexander_SURF2019.pdf (444.9Kb)
    Author
    Hoffman, Alexander; Stewart, Taryn; Brady, Keaton; Mundel, Samantha
    Date of Issue
    2019-04-25
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    URI
    https://scholars.carroll.edu/handle/20.500.12647/7179
    Title
    Site Specific Photoinitiated Release of Bromothymol Blue
    Abstract
    Delivery of pharmaceutical drugs to specific sites of the body would be beneficial for the treatment of cancer and other major ailments which affect singular areas of the body. There are promising possibilities being studied to determine their efficacy. Here is presented the investigation of the photoinitiated release of an indicator, acting as a drug, from a vesicle into an environment containing a reactant. In this experiment, spiropyran was integrated into Dipalmitoylphosphatitylcholine (DMPC) and 1’,3’,3’-Trimethylspiro[chromene-2,2’-indoline] (spiropyran) are the components of the carrier vesicles that surround bromothymol blue (BTB) in the sodium bicarbonate solution. Spiropyran is a photochromic compound that changes structure when exposed to UV-light.1
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