Simulated Macrophages And Resistance To Herpes Simplex Virus In Newborn Mice

Abstract

Peritoneal macrophages from adult mice failed to protect 24-48 hr. newborn mice from intraperitoneal infection with Herpes Simplex Type I. Macrophages stimulated with either proteose peptone or thioglycollate medium showed no more increased protection than unstimulated macrophages.