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    Immunological and Immunohistochemical Methods Used to Study Chromatin Neoantigens of Novikoff Hepatoma

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    Author
    Binette, Steven; O'Connor, Timothy
    Advisor
    James Manion; Rev. Joseph Harrington; Guido Bugni
    Date of Issue
    1980-04-01
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    URI
    https://scholars.carroll.edu/handle/20.500.12647/3331
    Title
    Immunological and Immunohistochemical Methods Used to Study Chromatin Neoantigens of Novikoff Hepatoma
    Type
    thesis
    Abstract
    The micro-complement fixation test was used to assay the potency and specificity of rabbit antisera to chromosomal antigens from Novikoff hepatoma and normal rat liver. The complement fixation titration patterns suggest the presence of only a few species of molecules bearing neochromatin antigens. A immunofluorescent technique was adapted to Novikoff hepatoma cells and resulted in the positive staining of Novikoff chromatin and negligible staining in normal rat liver cells.
    Degree Awarded
    Bachelor's
    Semester
    Spring
    Department
    Life & Environmental Sciences
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    • Life and Environmental Sciences Undergraduate Theses

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