Immunological and Immunohistochemical Methods Used to Study Chromatin Neoantigens of Novikoff Hepatoma

Loading...
Thumbnail Image
Authors
Binette, Steven
O'Connor, Timothy
Advisor
James Manion
Rev. Joseph Harrington
Guido Bugni
Editor
Date of Issue
1980-04-01
Subject Keywords
Publisher
Citation
Series/Report No.
item.page.identifier
Title
Immunological and Immunohistochemical Methods Used to Study Chromatin Neoantigens of Novikoff Hepatoma
Other Titles
Type
thesis
Description
Abstract
The micro-complement fixation test was used to assay the potency and specificity of rabbit antisera to chromosomal antigens from Novikoff hepatoma and normal rat liver. The complement fixation titration patterns suggest the presence of only a few species of molecules bearing neochromatin antigens. A immunofluorescent technique was adapted to Novikoff hepatoma cells and resulted in the positive staining of Novikoff chromatin and negligible staining in normal rat liver cells.
Sponsors
Degree Awarded
Bachelor's
Semester
Spring
Department
Life & Environmental Sciences