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    Valproic Acid In Epilepsy: Clinical And Adverse Effects

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    1979_SiddowayP_THS_0001141.pdf (5.017Mb)
    Author
    Siddoway, Paul
    Advisor
    Philip Pallister; James Manion; John Christenson
    Date of Issue
    1979-04-01
    Metadata
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    URI
    https://scholars.carroll.edu/handle/20.500.12647/3227
    Title
    Valproic Acid In Epilepsy: Clinical And Adverse Effects
    Type
    thesis
    Abstract
    The antiepileptic drug sodium valproate was studied in 19 epileptic patients with uncontrolled seizures of a generalized or partial type. Two-thirds of the patients experienced a reduction in seizure fre uency ranging from 33 to 100%. Adverse effects occurred in 7 (37%) patients and in 4 (21%) the drug had to be discontinued. The most serious adverse effects were platelet reduction and weight gain. Minor adverse effects (e.g. nausea, hair loss, SGOT elevation, ALKOP4 elevation) were always transient.
    Degree Awarded
    Bachelor's
    Semester
    Spring
    Department
    Life & Environmental Sciences
    Collections
    • Life and Environmental Sciences Undergraduate Theses

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