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    The Cytotoxic And Kinetic Effects Of Asynchronous Cells Following The Administration Of Vincristine

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    1984_FirpoM_THS_0001025.pdf (2.139Mb)
    Author
    Firpo, Meri
    Advisor
    James Manion; Rev. Joseph Harrington; Barry Ferst
    Date of Issue
    1984-04-01
    Metadata
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    URI
    https://scholars.carroll.edu/handle/20.500.12647/3161
    Title
    The Cytotoxic And Kinetic Effects Of Asynchronous Cells Following The Administration Of Vincristine
    Type
    thesis
    Abstract
    A growth curve was constructed for SCCVII-SF, a mouse squamous cell carcinoma cell line, in a culture of modified q-crle's medium. A toxicity curve was constructed for vincristine ,nd SCCVII-SF cells in the exponential phase of growth. Cells in mid-exponential phase were treated with a subtoxic level of vincristine for four hours. A count of mitotic cells was taken at intervals to determine whether vincristine caused a buildup of cells in mitosis after its removal. Results showed that cells continued to collect in mitosis for four hours after the removal of vincristine.
    Degree Awarded
    Bachelor's
    Semester
    Spring
    Department
    Life & Environmental Sciences
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    • Life and Environmental Sciences Undergraduate Theses

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