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dc.contributor.advisorRev. Joseph Harrington
dc.contributor.advisorJames Manion
dc.contributor.advisorRev. Robert Butko
dc.contributor.authorHolland, John
dc.date.accessioned2020-04-30T10:02:58Z
dc.date.available2020-04-30T10:02:58Z
dc.date.issued1984-04-01
dc.identifier.urihttps://scholars.carroll.edu/handle/20.500.12647/3158
dc.description.abstractPreliminary experimentation was performed to characterize the P3 human epithelial cell line for radiobiological research. Specifically, work was done to determine if the cell line should be used to evaluate mechanisms of radiation damage and repair as revealed by survival response experimentation and via the 6-thioguanine mutation assay. Growth analysis was performed as well as a 6-thioguanine toxicity study and a 6-thioguanine mutation expression time curve. Preliminary results were obtained from survival experiments following P3 cell irradiation with 50 KvP X-rays, 6^co gamma rays, and Janus Reactor fission spectrum neutrons with a mean energy of 0.86 MeV. These and preliminary results of 6-thioguanine resistance mutation frequency experiments utilizing Janus Reactor fission spectrum neutrons will be discussed.
dc.titlePreliminary Characterization Of The P3 Human Epithelial Cell Line For Radiobiological Reseach
dc.typethesis
carrollscholars.object.degreeBachelor's
carrollscholars.object.departmentLife & Environmental Sciences
carrollscholars.object.disciplinesCell Biology; Toxicology
carrollscholars.legacy.itemurlhttps://scholars.carroll.edu/lifesci_theses/416
carrollscholars.legacy.contextkey12492937
carrollscholars.object.seasonSpring
dc.date.embargo12/31/1899 0:00


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