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dc.contributor.advisorJohn Christenson
dc.contributor.advisorFr. Joseph Harrington
dc.contributor.advisorJohn Hart
dc.contributor.authorTruax, Allan
dc.date.accessioned2020-04-30T10:02:20Z
dc.date.available2020-04-30T10:02:20Z
dc.date.issued1987-04-01
dc.identifier.urihttps://scholars.carroll.edu/handle/20.500.12647/3092
dc.description.abstractAminoglycosides have been associated with the preferential loss of hair cells; first in the basal portion of the organ of Corti and later in the apical portion of the organ of Corti. One current hypothesis is that a direct correlation exists between the concentration of aminoglycoside in the hair cells and destruction of the hair cells. The results of this experiment indicated that there were no detectable differences in drug concentrations between the basal portions and the apical portions of the organ of Corti. Interpretation of these results suggests that the preferential loss of hair cells is not due to differences in drug concentrations between the basal and apical hair cells.
dc.titleA Study Of The Aminoglycoside-Induced Mechanisms That Cause Auditory Toxicity In Guinea Pigs
dc.typethesis
carrollscholars.object.degreeBachelor's
carrollscholars.object.departmentLife & Environmental Sciences
carrollscholars.object.disciplinesPharmacology; Toxicology
carrollscholars.legacy.itemurlhttps://scholars.carroll.edu/lifesci_theses/350
carrollscholars.legacy.contextkey12361849
carrollscholars.object.seasonSpring
dc.date.embargo12/31/1899 0:00


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