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    Pilus Antigenic Variation and Protein II Composition in the Outer Membrane of Neisseria gonorrhoeae, a Case History of Patient 016

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    1988_SolaJ_THS_000887.pdf (3.548Mb)
    Author
    Sola, James
    Advisor
    John Addis; Guido Bugni; Marilyn Schendel
    Date of Issue
    1988-04-01
    Metadata
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    URI
    https://scholars.carroll.edu/handle/20.500.12647/3066
    Title
    Pilus Antigenic Variation and Protein II Composition in the Outer Membrane of Neisseria gonorrhoeae, a Case History of Patient 016
    Type
    thesis
    Abstract
    In this study several male volunteers were infected with piliated gonococci expressing none of the pH proteins. Urine samples were collected from the patients twice daily until the patient developed clinical symptoms of gonorrhea. The samples from each volunteer were then analyzed in order to characterize how pII expression varied while being present in a human host. Pili were also examined for diferences in molecular weight. My role was to study the reisolated gonococci from patient 016. Pili were examined by epitope mapping, and the sequences of four pilin genes taken from the last urine sample were determined.
    Degree Awarded
    Bachelor's
    Semester
    Spring
    Department
    Life & Environmental Sciences
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    • Life and Environmental Sciences Undergraduate Theses

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