• Login
    View Item 
    •   Carroll Scholars Home
    • Life and Environmental Sciences
    • Life and Environmental Sciences Undergraduate Theses
    • View Item
    •   Carroll Scholars Home
    • Life and Environmental Sciences
    • Life and Environmental Sciences Undergraduate Theses
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Neutralization Of Agglutination On Chinese Hamster Ovary Cells By Pertussigen

    Thumbnail
    View/Open
    1988_VogelmanL_THS_000804.pdf (1.717Mb)
    Author
    Vogelman, Lee
    Advisor
    John Christenson; Jean Smith; Ruth Carrington
    Date of Issue
    1988-04-01
    Metadata
    Show full item record
    URI
    https://scholars.carroll.edu/handle/20.500.12647/3064
    Title
    Neutralization Of Agglutination On Chinese Hamster Ovary Cells By Pertussigen
    Type
    thesis
    Abstract
    Monoclonal antibodies specific for epitopes on the perstussigen molecule, s-1, were developed by the Fetuin-ELISA test, radioimmunoassays and Western Blott(27). Hybridoma fluids already established for specificity on s-2, s-4 and the undigested molecule were exposed to pertussigen to detect the neutralization of agglutination to Chinese Hamster Ovary (CHO) cells. The results showed that no appreciable neutralization occurred. Many more monoclonals need to be developed and tested to find the critical epitope or epitopes which cause agglutination to CHO cells. This research may provide a clue to the specific antigenic site which causes toxicity attributed to whooping cough in humans.
    Degree Awarded
    Bachelor's
    Semester
    Spring
    Department
    Life & Environmental Sciences
    Collections
    • Life and Environmental Sciences Undergraduate Theses

    Browse

    All of Carroll ScholarsCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    DSpace software copyright © 2002-2023  DuraSpace
    DSpace Express is a service operated by 
    Atmire NV