• Login
    View Item 
    •   Carroll Scholars Home
    • Life and Environmental Sciences
    • Life and Environmental Sciences Undergraduate Theses
    • View Item
    •   Carroll Scholars Home
    • Life and Environmental Sciences
    • Life and Environmental Sciences Undergraduate Theses
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Characterization of Chlamydial Major Outer Membrane Protein Variable Domain III

    Thumbnail
    View/Open
    1990_JasumbackM_THS_000587.pdf (2.752Mb)
    Author
    Jasumback, Michael
    Advisor
    John Addis; Rev. Joseph Harrington; Richard Lambert
    Date of Issue
    1990-04-01
    Metadata
    Show full item record
    URI
    https://scholars.carroll.edu/handle/20.500.12647/3050
    Title
    Characterization of Chlamydial Major Outer Membrane Protein Variable Domain III
    Type
    thesis
    Abstract
    We undertook this study to determine the immunoaccessibility of VD III of the major outer membrane protein (MOMP) of Chlamydia trachomatis. We used western blot, ELISA, and immunodot blot techniques to elucidate this characteristic of VD III. Using polyclonal, monospecific antibody developed to synthetic polypeptides, we demonstrated that VD III is not accessible to antibody in vitro. We also report the cross reactivity patterns of antiserum raised to three different serotypes of Chlamydia trachomatis. These cross reactivities will conceivably help to determine which variable domain sequences could be used in a subunit or recombinant vaccine candidate.
    Degree Awarded
    Bachelor's
    Semester
    Spring
    Department
    Life & Environmental Sciences
    Collections
    • Life and Environmental Sciences Undergraduate Theses

    Browse

    All of Carroll ScholarsCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    DSpace software copyright © 2002-2023  DuraSpace
    DSpace Express is a service operated by 
    Atmire NV