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    Screening for antibiotic, antifungal and antitumoral compounds in natural products extracted from freshwater sponges

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    2006_DonatoS_THS_000705.pdf (3.938Mb)
    Author
    Daehnke, Danielle
    Advisor
    John Addis; Sam Alvey; Murphy Fox
    Date of Issue
    2006-04-01
    Subject Keywords
    freshwater sponge, Ephydatia muelleri, Eunapius fragilis, Spongilla lacustris
    Metadata
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    URI
    https://scholars.carroll.edu/handle/20.500.12647/2931
    Title
    Screening for antibiotic, antifungal and antitumoral compounds in natural products extracted from freshwater sponges
    Type
    thesis
    Abstract
    The secondary metabolites of marine sponges include many bioactive products (e.g., ara-C) that have found uses in the health field. Even though freshwater sponges share many characteristics with their marine cousins, little is known about their secondary metabolites. This study looks at the effects of the secondary metabolites extracted from three freshwater sponge species on the survival of bacteria, fungi and brine shrimp. It found that none of the extracts were toxic to the bacteria or fungi. Preliminary results did, however, show that all three species tested were active against the brine shrimp. This study suggests that the secondary metabolites of freshwater sponges should be tested more extensively to see if they contain useful bioactive compounds.
    Degree Awarded
    Bachelor's
    Semester
    Spring
    Department
    Life & Environmental Sciences
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    • Life and Environmental Sciences Undergraduate Theses

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