• Login
    View Item 
    •   Carroll Scholars Home
    • Life and Environmental Sciences
    • Life and Environmental Sciences Undergraduate Theses
    • View Item
    •   Carroll Scholars Home
    • Life and Environmental Sciences
    • Life and Environmental Sciences Undergraduate Theses
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Exploring GluR2-Interacting Proteins in Caenorhabditis elegans

    Thumbnail
    View/Open
    BrothersJ_2016_Final.pdf (717.4Kb)
    Author
    Brothers, John
    Advisor
    Stephanie Otto-Hitt; William Parsons; Brandon Sheafor
    Date of Issue
    2016-04-01
    Metadata
    Show full item record
    URI
    https://scholars.carroll.edu/handle/20.500.12647/2751
    Title
    Exploring GluR2-Interacting Proteins in Caenorhabditis elegans
    Type
    thesis
    Abstract
    The expression of ?-3-hydroxy-5-Methlisoxaole-4-Propionic Acid Receptors (AMPARs) on the post-synaptic region of a neuron has direct impacts on many physiological functions of the brain, including learning and memory. Because AMPARs are Qirst assembled in the endoplasmic reticulum and later transported to the post-synaptic region of a neuron, understanding the mechanisms involved in AMPAR-trafQicking is crucial to understanding a variety of neuronal functions. The goal of this research was to investigate the role of the putative AMPAR-trafQicking proteins DLI-1, VDAC-1, SVOP-2, and DCN-2 on AMPAR-mediated behavior in the nematode Caenorhabditis elegans (C. elegans). Unfortunately, several technical issues prevented development of the constructs and behavioral assays needed to fully accomplish the goals of this study. Therefore, I am unable to discourse on the roles of DLI-1, VDAC-1, SVOP-2, and DCN-2 in AMPAR-mediated behavior in C. elegans.
    Degree Awarded
    Bachelor's
    Semester
    Spring
    Department
    Life & Environmental Sciences
    Collections
    • Life and Environmental Sciences Undergraduate Theses

    Browse

    All of Carroll ScholarsCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    DSpace software copyright © 2002-2023  DuraSpace
    DSpace Express is a service operated by 
    Atmire NV