Systematic Review of Deep Brain Stimulation as a Possible Treatment for Alzheimer's Disease
The goal of this systematic review is to assess current articles and their conclusions regarding the cognitive effects of Deep Brain Stimulation (DBS) on patients with Alzheimer’s Disease. Four of the seven reviewed studies found a strong correlation between increased cerebral metabolism and electrical stimulation as opposed to the typical decline in metabolism seen in AD. In addition this correlation, DBS was also found to have a significant effect on yielding the degradation of brain cells. DBS is found to be correlated with increased cerebral metabolism. This, however, did not associate with an improvement of cognition. Further research on the connection between cerebral metabolism and cognitive function is still required to allow for use of DBS as a treatment for Alzheimer’s.