How Gut Microbiome Interventions Affect Alzheimer's Symptoms, a Systematic Review
Objective: To review current literature concerning the effectiveness of gut microbiome interventions on Alzheimer’s symptoms and biomarkers.
Methods: Literature was gathered through PubMed and CINAHL and assessed for the effectiveness of gut microbiome interventions on Alzheimer’s symptoms and biomarkers. The interventions included were antibiotics, fecal microbiota transplantation (FMT), nutritional shifts, and probiotics.
Results: The majority of literature supported the stance that interventions to alter the gut microbiome have a favorable effect for Alzheimer’s patients. Antibiotics was the one intervention without full support from the literature. However, FMT, probiotics, and nutritional shifts had favorable results in both human and mice.
Conclusions: Gut microbiome interventions have shown promising results for Alzheimer’s patients in terms of symptoms and biomarkers. The interventions mentioned in this review should be researched further in order to provide additional treatment options.